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Author

O. H. Nielsen

2 papers indexed here

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Open access Sep 2026

Sphinganine as a novel stimulator of GLP-1 secretion.

AIMS/HYPOTHESIS Mechanisms of secretion of the gut hormone glucagon-like peptide-1 (GLP-1) remain incompletely understood yet are relevant for the pathophysiology and treatment of obesity and diabetes. Here, we set out to identify novel triggers. METHODS We started with using metabolomics on plasma samples from meal...

Mark M. Smits, A. Drzazga, Jarkko J. Lackman et al. · 0 citations
Open access Sep 2026

Single-cell immune repertoire atlas maps coordinated circulating adaptive immune states in inflammatory bowel disease

Single-cell studies have defined immune states in inflammatory bowel disease (IBD), but how adaptive receptor histories organize circulating immunity remains unclear. We generated a single-cell transcriptomic atlas of peripheral blood from 249 participants with Crohn’s disease, ulcerative colitis, or non-IBD control st...

J. Gubatan, Jia-Yu Ye, Christin Lund-Andersen et al. · 0 citations

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