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Review Open access Oct 2026

CAR T-Cell Therapy in Hematological Malignancies: Mechanisms, Innovations, and Challenges

Simple Summary Chimeric antigen receptor (CAR) T-cell therapy is a revolutionary immunotherapy that engineers a patient’s own immune T cells to specifically target and destroy malignant cells in hematological malignancies. This approach has transformed the treatment of relapsed acute lymphoblastic leukemia, lymphomas,...

Alaa A. A. Aljabali, Mohammad A. Obeid, A. Alqudah et al. · 0 citations
Jul 2026

Gastrodin mitigates cisplatin-induced cardiotoxicity in Swiss albino mice by restoring redox homeostasis and modulating the p62–Keap1–Nrf2 Axis

Gastrodin may have a protective activity against CP cardiotoxicity, primarily by restoring redox balance/energy status, suppressing inflammation and apoptosis, and modulating p62–Keap1–Nrf2 related gene expression.

A. Alqudah, E. Qnais, Yousra Bsieso et al. · 0 citations

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