Dosimetric and radiobiological evaluation of a spatially fractionated core-boost strategy in lung metastases within 5 mm of the esophagus: Single-center plan-comparison study.
For lung metastases lying within 5 mm of the esophagus, organ-at-risk dose limits often force the prescription below the ablative range, lowering biologically effective dose and tumor control. We evaluated whether a simultaneous integrated boost to the tumor core, rather than dose reduction, is dosimetrically and radio...