Author

O. Chiba-Falek

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Open access Sep 2026

Cellular transcriptomic signatures underpinning the heterogeneity of depression in Alzheimer's disease

This work investigated brain transcriptomic landscapes to gain insights into shared and divergent molecular and biological etiologies across LOAD and MDD.

Michael W. Lutz, Zhao-Hui Man, O. Chiba-Falek · Alzheimer's & Dementia · 0 citations

Open access Aug 2026

SNCA-targeted transcriptional repression therapy alleviates pathological and behavioral perturbations in a Parkinson's disease mouse model

In vivo proof-of-concept for SNCA-targeted transcriptional repression therapy in a PD-mouse model is provided and its further preclinical development toward investigational new drug enablement is supported.

Bernadette O'Donovan, Joseph E. Rittiner, Suraj Upadhya et al. · Neurotherapeutics · 0 citations