Prevalence of Metastatic Disease at Diagnosis among Men with Prostate Cancer in Africa: A Systematic Review and Meta-analysis
Metastatic Prostrate cancer has become a major concern to the public health and a silent threat to the African men, with several patients presenting at elevated stage of the disease. Thus, the study deployed a systematic review approach as well as meta-analyses to examine the prevalence of the disease at diagnoses stage among the African men that have prostate cancer. Eligible search of studies at metastatic status at presentations were explored. The outcome shows a high prevalences of metastatic prostate cancer at diagnoses within the African men with affected parts being the bone and lymph nodes. Furthermore, it was observed that late presentation usually occur which could be due to limited screening provisions, low education and barriers to health care facilities. These findings suggest the urgent need for adequate early detection program, improvement in access to diagnostic services as well as improved cancer care system so as to reduce the stress of elevated metastatic prostate cancer, thus, improving survival of African men.