O. Alomarı

H3K27-altered diffuse midline glioma of the adult thoracic spinal cord: A case report with literature review and clinical insights

Background: Primary spinal cord gliomas are rare, with adult-onset diffuse midline glioma (DMG), H3K27-altered, representing an even smaller and highly aggressive subset. Recently classified as a World Health Organization (WHO) Grade 4 entity, these tumors typically arise in midline structures and carry a poor prognosi...

Cervicothoracic dumbbell ganglioneuroblastoma with spinal canal involvement and bone marrow metastasis: a case report and systematic review.

Systemic and local dysregulation of the complement system in glioma: a comprehensive systematic review.

Intrasellar Cavernous Malformations: Two Case reports with A Systematic Review of Clinical Features, Surgical Management, and Outcomes.

ICMs are deceptive vascular lesions that require careful vigilance to minimize significant intraoperative hemorrhage and although complete resection is often technically challenging, tailored surgical strategies can achieve favorable functional outcomes.

Non-invasive brain stimulation in amyotrophic lateral sclerosis: a systematic review and meta-analysis of transcranial direct current stimulation and transcranial magnetic stimulation.

BACKGROUND Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder with limited disease-modifying treatments. Noninvasive brain stimulation techniques have been investigated as potential neuromodulatory interventions targeting cortical hyperexcitability in ALS. OBJECTIVE To systematically eval...

Pure endoscopic resection of brainstem cavernous malformations: a systematic review of current evidence and future directions

Purely endoscopic resection of BCMs is a technically feasible and effective treatment modality, particularly for ventral and ventromedial pontine lesions, and offers high GTR rates and favorable neurological recovery while avoiding the brain retraction associated with open microsurgery.

Surgical outcomes and prognostic factors in traumatic optic neuropathy: a systematic review and meta-analysis of the endoscopic optic nerve decompression.

While pooled data supports surgical decompression as an effective intervention, future multicenter randomized controlled trials are essential to refine patient selection criteria, clarify the role of adjunctive steroids, and establish standardized protocols.