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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

O. Allela

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Review Oct 2026

Hypoxia-induced epigenetic reprogramming of cancer stem cells: Linking stemness, metastasis, and therapy resistance.

Hypoxia is a defining feature of the solid tumor microenvironment and a central driver of cancer-stem-cell (CSC) biology, yet the epigenetic mechanisms linking oxygen deprivation to stemness, metastasis, and therapy resistance remain fragmented across the literature. This review synthesizes that evidence into a unified...

M. Al-khreisat, Rustam Narzikulov, O. Allela et al. · 0 citations
Review Jul 2026

Peptide Loading Complex in Cancer: From Peptide Translocation, Editing, and Loading into MHC-I to a Potential Therapeutic Target

An overview of the PLC as a major determinant of tumor immune escape and a potential therapy target is provided and existing or evolving therapeutic approaches to recover/reprogram PLC functions are explored.

O. Allela, Abdulkareem Shareef, Hayder Naji Sameer et al. · 0 citations

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