Vitamin D deficiency is highly prevalent in obesity and has been linked to insulin resistance, atherogenic dyslipidemia, and increased cardiometabolic risk. Whether vitamin D deficiency in obese individuals is driven predominantly by glycemic category (euglycemia, prediabetes, type 2 diabetes mellitus T2DM) or by...
O. Abdelkarem, Nagla Usama, Amr E. Ahmed et al.· Clinical Chemistry· 0 citations
Von Hippel–Lindau disease (VHL) is an autosomal dominant cancer predisposition syndrome caused by pathogenic variants in the VHL gene, leading to impaired degradation of hypoxia-inducible factor (HIF) and dysregulated angiogenic signaling. Missense variants are commonly associated with pheochromocytoma-predominan...
O. Abdelkarem, M. Alam, M. Bhat et al.· Clinical Chemistry· 0 citations
An integrated framework for understanding how NK-DC interactions establish, maintain, and potentially restore immune homeostasis is proposed, in which Tregs act as downstream regulatory partners that reinforce peripheral tolerance rather than as equivalent components of the central NK-DC axis.
A. Hemdan, Nagla Usama, O. Abdelkarem· Immunology Research and Pers...· 0 citations
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