Open access
Jul 2026
How Functional Variants Reconfigure the Rac2 Conformational Landscape
Using molecular dynamics simulations, this work provides a high-resolution, mechanistic framework for understanding how localized perturbations in the switch loops landscape dictate systemic cellular outcomes.
Nurit Haspel, H. Jang, R. Nussinov
· Journal of Physical Chemistr... · 0 citations