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Author

Nuo Xu

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Oct 2026

zDHHC11 is a Common Palmitoyltransferase Regulating Microglia-Mediated Neuroinflammation across Neurodegenerative Diseases.

PURPOSE Microglia-mediated neuroinflammation is a shared feature across Alzheimer's disease (AD), Parkinson's disease (PD), and diabetic cognitive impairment (DCI), but the convergent molecular mechanisms remain unclear. This study investigated whether protein S-palmitoylation serves as a common regulator of microglial...

Hai-Ting Luo, Dian-Dian Jiang, Zhi-Yuan Hao et al. · 0 citations
Review Open access Aug 2026

Neuron-Derived Neuroinflammation in Neurodegenerative Diseases: Mechanisms and Intervention Prospects.

Intervention strategies that shift from targeting peripheral immune and glial cells to regulating neuron-derived immunity are systematically integrated, thereby providing a new theoretical framework for overcoming current clinical limitations and identifying effective therapeutic targets for the prevention and treatmen...

Jie Bu, Xuan Nie, Haiting Luo et al. · 0 citations
Review Open access Aug 2026

Emerging targeted therapies for primary immune thrombocytopenia: novel agents, combination strategies, and future directions

This article analyses recent therapeutic trials with Bruton’s tyrosine kinase inhibitors, splenic tyrosine kinase inhibitors, and neonatal Fc receptor antagonists, demonstrating an improvement in platelet counts and patients’ quality of life.

Zhen Wang, Wu-Xia Yang, Nuo Xu et al. · 0 citations

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