m6A writer METTL14 restricts Mycobacterium tuberculosis infection by promoting TAX1BP1-mediated autophagy in macrophages.
N6-methyladenosine (m6A) modification plays a crucial role in regulating immune responses against Mycobacterium tuberculosis (Mtb) infection, but the underlying mechanisms remain unclear. Here, we analyzed m6A regulatory gene expression in GEO dataset GSE139825 and validated the finding in THP-1-derived macrophages. Bi...