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Open access Sep 2026

DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography.

Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography is also frequently tested for its ability to remove viruses. Although protein A sp...

Lukas Döring, S. Schubert, Nora Roos et al. · 0 citations

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