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Author

Noor H. Naser

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Aug 2026

In silico study of thiazole-based amino coumarin derivatives with promising carbonic anhydrase inhibitory activity.

Findings suggest that the produced 6-aminocoumarin derivatives, specifically compound IIId, could serve as promising, effective inhibitors of carbonic anhydrase with potential anti-cancer activity targeting the carbonic anhydrase IX enzyme.

Alaa H. Fadel, Noor H. Naser · 0 citations
Open access Aug 2026

Design, synthesis, characterization, molecular docking, MM-GBSA analysis, and molecular dynamics simulation of novel coumarin-hydrazone derivatives as potential carbonic anhydrase inhibitors

Overall, these findings identify coumarin-hydrazide-hydrazone derivatives as computationally prioritized scaffolds that require biochemical CA inhibition and cellular validation before any anticancer conclusion can be drawn.

Ayuub J. Mohammed, Noor H. Naser, Wathiq Al-hachami · 0 citations

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