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Nobutaka Shimizu

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Open access Nov 2026

Durable Complete Response to Pembrolizumab for Postoperative Nodal Recurrence of Lynch Syndrome–Associated Upper Tract Urothelial Carcinoma: A Case Report

ABSTRACT Introduction Germline mutations in mismatch repair genes cause Lynch syndrome and are associated with upper tract urothelial carcinoma (UTUC). Tumors with deficient mismatch repair (dMMR) or microsatellite instability–high (MSI‐H) may respond favorably to immune checkpoint inhibitors. Case Presentation A 54‐ye...

Kaya Atagi, Shinkuro Yamamoto, Nobutaka Shimizu et al. · 0 citations

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