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Author

Nitish Kumar

Texas Christian University

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Review Sep 2026

Coumarin derivatives combating antibacterial resistance: molecular modeling-driven insights and comprehensive SAR elucidation targeting DNA gyrase and topoisomerase IV.

Overall, the collective evidence establishes coumarin as a highly adaptable scaffold for the development of next-generation antibacterial agents and highlights integrated structure-based design, dual-target inhibition, and comprehensive biological validation as key priorities for future medicinal chemistry research.

Aanchal Khanna, Karanvir Singh, Alok Raj et al. · 0 citations

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