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Author

Nisha Bhattarai

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Open access Aug 2026

Bioinformatic Characterization of Regulated IRE1α-Dependent Decay (RIDD) in Heart Failure

Inositol-requiring enzyme 1α (IRE1α) is a canonical signaling factor in the unfolded protein response (UPR). In addition to this essential role (which prevents the accumulation of misfolded proteins in the endoplasmic reticulum), the endoribonuclease activity of IRE1α targets multiple mRNAs for degradation through a pr...

Nisha Bhattarai, Angelina Kendi, M. Stoner et al. · 0 citations

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