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Orchestrating multiple agents on a complex task requires reconciling local subtask execution with global task planning. Dynamic dispatch approaches provide execution flexibility but do not explicitly model subtask hierarchies or dependencies, while predefined workflows impose this structure but fix the decomposition be...
Background and purpose To evaluate the efficacy and safety of endovascular treatment (EVT) versus standard medical therapy (SMT) in patients with progressive large vessel occlusion (LVO) presenting 24–72 h after onset. Methods We retrospectively analyzed patients with progressive LVO and perfusion mismatch (tissue wind...
Apollo did not reach the Moon merely because its engineers could solve difficult equations. It succeeded by turning a distant ambition into a mission architecture of explicit objectives, simulation, verification, and repeated correction. AI now faces a similar transition: frontier models can solve difficult tasks once...
Scientific agents increasingly analyze data, execute code, and produce research artifacts, yet most benchmarks emphasize final answers, isolated programs, or a single domain. We introduce FrontierChallenge, a cross-domain benchmark comprising 300 end-to-end scientific workflows. In this paper, we release and evaluate 9...
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