Entropy-Encoded Electronic Reconstruction in High-Entropy Nanozymes Enables Cofactor-Free Monooxygenase-Like Catalysis.
Flavin-dependent monooxygenases (FMOs) catalyze redox reactions central to antibiotic degradation and metabolic detoxification, yet replicating their intricate cofactor-dependent electron transfer in synthetic systems has remained elusive. Here, we report an electronic modulation strategy that enables cofactor-free FMO...