The mitochondrial chaperone HSPD1 folds MTHFD2 independently of its co-chaperone HSPE1
Acquiring new cellular states entails metabolic reprogramming driven by changes in the expression of cytosolic and mitochondrial metabolic enzymes. Most mitochondrial proteins are synthesized in the cytosol and imported into the mitochondria in a linear form, after which they are folded by a network of mitochondrial ch...