Nikolina Šoštarić

Conformational selection and redox-dependent destabilization in the IspG–FldA electron transfer complex

Electron transfer between proteins is mediated by transient complexes that sample many binding orientations, only a subset productive. Protein electron carriers (PECs) form such complexes with diverse enzymes across central metabolism, yet no general framework predicts which PEC–enzyme pairs will function. A representa...