Author

Nicolle H. Packer

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Open access Oct 2026

Streptococcus pyogenes transforms the salivary proteome during controlled human infection

Streptococcus pyogenes (Group A Streptococcus, GAS) is among the leading causes of infectious mortality and primarily manifests as acute pharyngitis. The development of an effective vaccine continues to be hindered by an incomplete understanding of the host immune response, particularly in the oropharynx. Here, we prov...

Anuk D. Indraratna, D. Cox, P. Das et al. · bioRxiv · 0 citations

Open access Oct 2026

Multi-Site Quantitative Benchmarking of Neu5Gc-Bearing N-Glycans Using Matrix-Matched LC-MS calibration.

It is found that the DMB-LC-FLR assay's specificity and sensitivity were insufficient for Neu5Gc detection in human samples due to noise overwhelming the Neu5Gc signal, and LC-MS confidently resolved Neu5Gc signals from noise, even at low abundance.

Nicholas J. DeBono, Edward S. X. Moh, J. Poole et al. · Glycobiology · 0 citations