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Summary Background The cardiovascular-kidney-liver-metabolic (CKLM) framework represents the multi-organ interplay of systemic metabolic disorders that drive the global burden of cardiovascular diseases (CVD). Methods This study is a descriptive epidemiological analysis of the Global Burden of Disease Study 2023 that e...
Resistant hypertension, defined as blood pressure above target despite treatment with at least three antihypertensive agents (including a diuretic) or controlled blood pressure requiring four or more medications, affects over 140 million individuals globally and confers increased risks of heart failure, stroke, and chr...
The improvements in cardiovascular risk factor exposure in the Asia–Pacific have been offset by population growth and ageing, and the metabolic-centric pattern in risk factors demands for strategies in tackling the region's high priority metabolic risk factor targets.
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