Skip to content
Log in
Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Nicholas W. Hughes

h-index 7 View on Semantic Scholar

We have 1 of 19 papers

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Aug 2026

Efficient exploration of sequence space enables rapid generation of functional genome editors

An approach to create novel, functional proteins through the integration of deep mutational scanning, structural analysis, and evolutionary mining within prompts for a generative protein language model (PLM) is described and the utility of this approach is demonstrated with the generation of novel compact RNA-guided nucleases.

Nicholas W. Hughes, Sourab Kulkarni, Grant Goldman et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.