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Nicholas Magazine

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Open access Jul 2026

Intranasal exposure to SARS-CoV-2 spike protein induces Th2 and Th17 cell-associated pulmonary immunopathology 2258252

Intramuscular mRNA vaccines show superior safety, while spike contains epitopes capable of driving Th2- and Th17-mediated pathology, highlighting the need to refine spike antigens and booster strategies for durable, safe protection.

Tian-Yi Zhang, Nicholas Magazine, Lamis El-Baz et al. · Journal of Immunology · 0 citations