Nezahat Gokce Ozsamur

Histone Deacetylase-Activatable BODIPY-Based G-Quadruplex Stabilizer Significantly Reducing Colon Cancer Proliferation

G-Quadruplexes are non-canonical nucleic acid structures mostly located in gene promoters and telomeres. Although G4 stabilization with synthetic/natural ligands is a promising anticancer approach, dense distribution throughout the genome restricts their selective targeting. Additionally, cationic G4 ligands are wide...