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Author

Neelamegam Rameshkumar

2 papers indexed here

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Open access Oct 2026

Natural Products as MexB‐specific Efflux Pump Inhibitors Against Pseudomonas aeruginosa

Antimicrobial resistance (AMR) remains a critical global health challenge, with the RND‐type MexAB–OprM efflux system of Pseudomonas aeruginosa playing a central role in intrinsic multidrug resistance (MDR) through the active extrusion of diverse antibiotics. In this study, we screened natural product libraries t...

Adarsha Sarmah, Anto Antony Selvaraj, Neelamegam Rameshkumar et al. · 0 citations
Open access Sep 2026

Integrated Effects of Digestion Strategy and LC Gradient Architecture Define Host Cell Protein Detectability in CHO Null Harvests

Accurate characterization of host cell proteins (HCPs) is critical for biologics development, yet analytical outcomes are strongly influenced by the digestion strategy and chromatographic design. Here, we systematically evaluated digestion parameters, including digestion mode, enzyme ratio, and incubation time, togethe...

Paresh Tank, Fatima D'Souza, K. Nagarajan et al. · 0 citations

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