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Author

Navid Dastyafteh

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3 papers indexed here

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Oct 2026

New hybrid molecules with 2,3,4,9-tetrahydro-1H-carbazol-1,3,4-oxadiazole-N-phenylacetamide framework as potent cholinesterase inhibitors.

AIMS In this study, new 2,3,4,9-tetrahydro-1H-carbazol-1,3,4-oxadiazole-N-phenylacetamide hybrids 8a-n as potential dual inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) for the treatment of Alzheimer's disease (AD) were introduced. METHODS The target compounds were designed using a molecula...

Reza Hassanzadeh Dostkoh, Navid Dastyafteh, Aida Iraji et al. · 0 citations
Open access Sep 2026

Design, Synthesis, and Evaluation of New 1,4‐Naphthoquinone‐1,2,3‐triazoles as Antimalarial Agents

A new series of compounds was evaluated as prospective in vitro antimalarial agents against the chloroquine‐sensitive 3D7 and chloroquine‐resistant K1 strains of Plasmodium falciparum, and the compound bearing a 4‐chloroaryl moiety was the most active against P. falciparum.

Lina Rezainia, M. Sayahi, Eisa Kaveh Vernousfaderani et al. · 0 citations
Aug 2026

Design, synthesis, and in vitro/in vivo evaluation of novel diphenyl-1,2,4-triazine-3-yl-thioacetamide-chalcone hybrids as potent α-glucosidase inhibitors targeting type 2 diabetes.

Findings identify compound 9b as a promising lead α-glucosidase inhibitor with potent in vitro and in vivo antihyperglycemic activity, warranting further investigation for the treatment of type 2 diabetes.

Elika Salehi Ghalehsefid, Mohammad Halimi, Hassan Mohammadi et al. · 0 citations

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