Author

Nathan Salomonis

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Open access Aug 2026

A Conversational Multi-Agent AI System for Integrated Multi-Omics Analysis and Biomedical Discovery

LungChat is deployed as a hierarchical multi-agent architecture in which a supervisor decomposes natural-language questions into parallel, tool-grounded tasks spanning single-cell and spatial analyses, literature and clinical-trial synthesis, and drug repurposing.

Pankaj Rajdeo, S. Asanuma, Michal Kouril et al. · bioRxiv · 0 citations

Review Open access Aug 2026

Targeting splicing-derived neoantigens for precision cancer immunotherapy

This review integrates current understanding of the biological origins, immunological barriers, target classes of splicing neoantigens, and the technologies that enable their advancement in cancer immunotherapy to produce two major classes of immunotherapeutic targets.

Mu-Tian Tang, H. L. Grimes, Nathan Salomonis · Frontiers in Immunology · 0 citations

Open access Jul 2026

The m6A-mediated epi-transcriptomic dysregulation drives synaptic dysfunction in fragile X syndrome.

It is demonstrated that FMRP deficiency drives the aberrant translational upregulation of core m6A writers, a causal relationship definitively validated using CGG-corrected isogenic control lines and suggest a promising avenue for m6A-targeted therapies.

Lu Lu, Avijite Kumer Sarkar, Lan Dao et al. · Molecular Psychiatry · 0 citations