Open access
Sep 2026
Functional annotation of insulin-responsive genes in human adipocytes reveals PLCXD1 as a lipid storage regulator
Insulin-driven gene regulation is central to adipocyte function, but the roles of many of these genes in lipid metabolism remain unclear. Here, we integrate three transcriptomic datasets to identify insulin-responsive genes and define their functions in human adipocytes using a multiparametric lipid turnover screen. Ou...
Scott Frendo-Cumbo, Danae Zareifi, Joëlle Bigay et al.
· Nature Communications · 1 citation