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Author

Nannan Wang

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Open access Oct 2026

CD73-targeted CAR-NK cell therapy displays potent antitumor activity and translational potential in relapsed/refractory lung adenocarcinoma

Relapsed/refractory (R/R) lung adenocarcinoma (LUAD) remains a clinical challenge with limited therapies and poor prognosis. CAR‑NK cell therapy has shown promise in solid tumors, but its efficacy is limited by both the availability of effective targets and the immunosuppressive tumor microenvironment. CD73 (NT5E), hig...

Qian-Qian Liu, Qi-Fei Dong, Yi-Mei Chen et al. · 0 citations
Review Open access Aug 2026

The Role of Alternative Splicing in Lung Cancer: Mechanisms, Regulators, and Therapeutic Implications

This review summarizes the multifaceted roles of AS in lung cancer biology, highlighting its contributions to tumor evolution, metastatic dissemination, and treatment resistance and its potential implications for biomarker discovery and precision therapeutic strategies targeting splicing dysregulation.

Lingrui Shang, Nannan Wang, Qianqian Liu et al. · 0 citations

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