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Nanasaheb D. Thorat

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Review Open access Sep 2026

Effector-cell-engaging bispecific antibodies for cancer therapeutics: engineering precision immunity.

This review outlines the evolution of effector-cell-engaging bsAb formats, such as BiTEs, DARTs, TandAbs and IgG-like constructs, along with engineering strategies to enhance Fc function, valency, half-life, safety and efficacy.

A. Gholap, P. Khuspe, Darshana Morankar et al. · 0 citations

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