Open access
Sep 2026
Paeoniflorin prevents acute graft-versus-host disease while preserving graft-versus-tumor effects
Findings support PF as a potential prophylactic candidate for allo-HSCT through coordinated regulation of donor T cell responses, inflammatory mediators, hematopoietic reconstitution, intestinal barrier injury, apoptosis, and gut microbiota, while preserving GVT activity.
Xing-Yu Wan, Nan Li, Yang Gou et al.
· Frontiers in Immunology · 0 citations