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Author

Nallusamy Duraisamy

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Review Aug 2026

Engineering CRISPR nanoplatforms to deplete cancer stem cells: Delivery checkpoints, target plasticity, and clinical viability.

This review reframes CSC-directed CRISPR nanomedicine as an integrated design problem and examines why target plasticity defeats static single-marker targeting; the sequential delivery checkpoints spanning blood stability, organ selection, tumor penetration, CSC recognition, endosomal escape, and productive editing; an...

Selvakumar Chandrasekaran, Nallusamy Duraisamy, Manjunathan Jagadeesan et al. · 0 citations

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