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Najmuddin Ansari

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Oct 2026

Asymmetric Access to Spirobenzofuran Oxindoles via Organocascade Reaction of Unprotected 3-Chlorooxindoles with 2-Hydroxy-β-Nitrostyrenes.

A highly enantioselective methodology has been developed to access oxindole-fused spiro dihydrobenzofuran, applicable to a protecting-group-free reactant, with high bond efficiency (1 new C-C and 1 C-O bond) and two contiguous stereocenters. Gram-scale and stereodivergent synthesis without compromising yield and select...

Manju Devi, Najmuddin Ansari, Ravi P. Singh · 0 citations

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