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Nai-Wen Chang

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Open access Sep 2026

MCseg: AI agent-guided workflow search for no-code cell segmentation and transcript attribution in spatial transcriptomics

Cell-level analysis of high-resolution spatial transcriptomics depends on accurate segmentation and transcript assignment, yet current workflows often trade transcript capture for boundary purity and can require substantial image-analysis expertise. We developed MCseg, a downloadable no-code platform whose fixed segmen...

C. Chan, Nai-Wen Chang, Chia-Yi Wang et al. · 0 citations
Sep 2026

Contact hypersensitivity promotes hair regeneration through SPP1-secreting macrophages.

Allergic contact dermatitis, or contact hypersensitivity (CHS), is a pathological adaptive immune response that paradoxically induces hair regeneration, yet its underlying mechanisms remain unclear. We integrated high-resolution spatial transcriptomics and single-cell RNA sequencing to map the intricate interactions be...

Kai-Rong Huang, Nai-Wen Chang, K. Tai et al. · 0 citations
Open access Jul 2026

Benchmarking large language models for de-identification of electronic health record notes

It is indicated that while fine-tuned LLMs offer superior accuracy, the observed performance variability across heterogeneous electronic health record sources poses significant technical challenges.

O. Panchal, Nai-Wen Chang, Zixiang Zhao et al. · 0 citations

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