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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Na Li

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Open access Aug 2026

Functional and mechanistic characterization of the phosphatidyl-myo-inositol mannosyltransferase PimA from Mycobacterium tuberculosis: implications for anti-tuberculosis drug development

Human-adapted Mycobacterium tuberculosis (Mtb) also infects animals and transmits zoonotically, threatening public health. The cell wall glycolipids lipoarabinomannan and lipomannan are essential virulence factors of Mtb. Phosphatidyl-myo-inositol mannosyltransferase PimA catalyzes a key step in their biosynthesis and...

Da-Feng Liu, Hua-Shui Deng, Xinbao Liu et al. · 1 citation

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