Genetic risk affect prognosis of coronary heart disease. High platelet reactivity(HPR) under antiplatelet treatment is associated with increased risks of adverse cardiovascular events.
Our study aims to explore whether combining polygenic risk and HPR can provide incremental predictive value for acute myoc...
Y. Yao, N. Xu, X.-F. Lu et al.· European Heart Journal· 0 citations
This meta-analysis suggests that high Lp(a) levels are associated with several imaging-defined high-risk coronary plaque features, with the most robust evidence observed for OCT-derived TCFA and plaque rupture.
J. Zhang, Yang Tang, Y. Cao et al.· International Journal of Car...· 0 citations
Background Inflammation plays a crucial role in adverse outcomes of coronary artery disease. NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome activates 2 classical pathways: interleukin-1β (IL-1β)/IL-6/high-sensitivity C-reactive protein (hsCRP) and IL-18/IL-6/hsCRP. However, the predicti...
Jia-Wen Li, Xiao-Zeng Wang, Zhen-Yu Liu et al.· JACC: Asia· 1 citation
Chronic inflammation and insulin resistance (IR) are key drivers of cardiovascular disease (CVD); however, their joint impact on cardiovascular risk remains poorly understood.
Meng-Lu Liu, N. Xu, Geng-Yu Sha et al.· Diabetes, obesity and metabo...· 0 citations
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