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Open access Oct 2026

Combining polygenic risk score and high platelet reactivity for incremental predictive value of acute myocardial infarction in patients with coronary artery disease with 10-year follow-up

Genetic risk affect prognosis of coronary heart disease. High platelet reactivity(HPR) under antiplatelet treatment is associated with increased risks of adverse cardiovascular events. Our study aims to explore whether combining polygenic risk and HPR can provide incremental predictive value for acute myoc...

Y. Yao, N. Xu, X.-F. Lu et al. · 0 citations
Review Open access Sep 2026

Association of Elevated Lipoprotein(a) levels with vulnerable plaque features assessed by multimodality coronary imaging in patients with coronary artery disease: A systematic review and Meta-analysis

This meta-analysis suggests that high Lp(a) levels are associated with several imaging-defined high-risk coronary plaque features, with the most robust evidence observed for OCT-derived TCFA and plaque rupture.

J. Zhang, Yang Tang, Y. Cao et al. · 0 citations
Open access Oct 2026

Combined Effects of Biomarkers in NLRP3 Inflammasome Axis and Cardiovascular Outcomes in Multivessels Disease

Background Inflammation plays a crucial role in adverse outcomes of coronary artery disease. NOD-like receptor family pyrin domain-containing protein 3 (NLRP3) inflammasome activates 2 classical pathways: interleukin-1β (IL-1β)/IL-6/high-sensitivity C-reactive protein (hsCRP) and IL-18/IL-6/hsCRP. However, the predicti...

Jia-Wen Li, Xiao-Zeng Wang, Zhen-Yu Liu et al. · 1 citation

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