Author

Nicholas Watkins

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Open access Sep 2026

Membrane Disruption and Charge Neutralization Drive Synergy Between LL37-Derived Peptides and Polymyxins Against E. coli

The study demonstrates that human-derived AMP LL37 and its fragments enhance the activity of conventional antibiotics against E. coli through membrane disruption and charge neutralization, as evidenced by the FICI values.

Wen-Xu Han, N. Watkins, T. Camesano · Biomolecules · 0 citations