Social behaviour is a heritable trait linked to well-being and mental health, yet it varies across social context, including social domains, informants and development, which may shape its underlying genomic architecture. Here, we conducted a genome-wide meta-regression meta-analysis of social behaviour from infancy to...
L. de Hoyos, Fenja Schlag, Sanjeevan Jahagirdar et al.· Nature Human Behaviour· 0 citations
Many AD pQTLs in CSF were enriched in neuroimmune activation, suggesting a genetic basis for neuroimmune dysregulation in AD, and how genetic variation shapes protein expression in the central nervous system is highlighted.
L. Reus, Chen-Yang Jiang, N. Vilor-Tejedor et al.· Molecular Neurodegeneration...· 0 citations
By analysing genome-wide data across 62 diseases, longevity and fertility, it is shown that disease-risk alleles are generally associated with reduced longevity and increased fertility, while alleles that increase both fertility and disease risk have been favoured by natural selection.
Eva Brigos-Barril, Claudia Vasallo, X. Farré et al.· Nature Ecology & Evolution· 2 citations
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