Author

N. Thomaidis

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Open access Sep 2026

Development and Validation of a Cost-Effective and Sensitive UHPLC-ESI-MS/MS Method for Vitamin B12 Determination in Yogurt

The accurate determination of vitamin B12 in fortified food products presents considerable analytical challenges due to its low concentrations (μg kg –1) and its binding to proteins in dairy products. This study aimed to develop a reliable and accurate method for determining vitamin B12 in yogurts that offers a robust,...

M. Katsa, A. Panara, Evagelos Gikas et al. · Analytica · 0 citations

Review Open access Sep 2026

Glymphatic Dysfunction Across Neurological disorders: Links to Neurodegeneration, Inflammaging, Gut–Brain Signaling, and Physiological Modulators

The glymphatic system is a brain-wide perivascular network that facilitates cerebrospinal-fluid–interstitial-fluid exchange and the clearance of metabolic waste. Growing experimental and clinical evidence suggests that glymphatic dysfunction may represent a convergent pathophysiological feature associated with aging, n...

Konstantinos I. Voumvourakis, N. Thomaidis, Eleni Sideri et al. · Biomedicines · 0 citations

#protein folding Open access Sep 2026

Harnessing coumarin privilege to achieve potency and selectivity: hypoxia-targeted alkyl coumarin-tethered phenyl quinazolinones as dual hCA IX/HSP90α inhibitors with chemosensitizing activity

A series of alkyl coumarin-tethered phenyl quinazolinones were rationally designed and synthesized as hypoxia-targeted dual hCA IX/HSP90α inhibitors, exhibiting potent, highly selective inhibition of hCA IX (in the nanomolar range), while displaying negligible activity against the off-target isoforms hCA I and II.

Amal S. Elgohary, Mervat H. El-Hamamsy, N. Sharafeldin et al. · RSC Advances · 0 citations