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Review Sep 2026

Orexin pathway modulation in narcolepsy: from Autoimmune mechanisms to nanotechnology enabled therapeutic delivery.

Narcolepsy is a long-term brain disorder caused by disrupted orexin signaling. Orexin neurons sit in the hypothalamus and control the sleep-wake cycle; damage to these neurons leads to narcolepsy. Early evidence pointed to an autoimmune attack on orexin neurons as the main cause. Current treatments - stimulants, antide...

Muhammad Irfan, N. Shahid, Ayesha Nasar et al. · 0 citations
Open access Sep 2026

A Prospective Observational Assessment of Postoperative Pain and Recovery Following Elective Surgery

Background:  Elective surgery is often associated with postoperative pain, which can delay recovery, prolong hospital stay, and reduce patient satisfaction. Early recognition and management of pain are essential for optimal postoperative recovery. The study evaluated postoperative pain and recovery after elective surge...

Fatima Qayyum, N. Shahid, Ahmed Al-Nasar et al. · 0 citations
Open access Sep 2026

Patterns and Risk Factors Associated with Postoperative Nausea and Vomiting Among Surgical Patients

Optimize anesthetic care, opioid-sparing analgesia, and risk-based antiemetic prophylaxis can lower the risk of PONV, and approaches for optimizing postoperative comfort, safety, and recovery explored by future multicentered research.

Fatima Qayyum, N. Shahid, Ahmed Al-Nasar · 0 citations

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