Open access
Aug 2026
Tumor-Responsive Delivery of 5‑Fluorouracil from a Redox-Triggered Supramolecular Gelator
A 5-FU covalent conjugate with the self-assembling, heterochiral tripeptide DLeu-Phe-Phe (lFF) via a redox-sensitive linker (5-FU-SS-lFF) yields supramolecular hydrogels with rheological properties similar to those of lFF hydrogels and enables 5-FU release under reducing conditions, such as those present in the tumor m...
M. Mihajlovic, Milos Mihajlovic, Paola Alletto et al.
· Bioconjugate chemistry · 0 citations