N. Q. Ngô

Reductive Catalyst Regeneration Enables the General Cu-Catalyzed Atom Transfer Radical Addition with Primary Alkyl Halides.

Primary alkyl halides are poor coupling partners in most atom transfer radical addition (ATRA) reactions due to their propensity to undergo off-cycle radical termination pathways, which lead to catalyst deactivation. Herein, we overcome this challenge in the Cu-catalyzed ATRA reaction though the addition of 1,1'-azobis...