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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

N. Pinpathomrat

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Open access Oct 2026

Design of a tetravalent dengue vaccine incorporating T-cell epitopes from NS3 and NS5 proteins and B-cell epitopes from the envelope protein using an immunoinformatics approach

Dengue virus remains a major global health threat due to its four antigenically diverse serotypes and limited treatment and vaccine options. This study aimed to design and evaluate a rational tetravalent multi-epitope vaccine capable of eliciting broad cross-serotype immune responses against dengue virus. An immunoin...

Theerawat Dobutr, Pemikar Srifa, N. Pinpathomrat · 0 citations
Open access Jul 2026

Dual Mechanisms of Apigenin and Luteolin Against Dengue Virus Serotype 2: Allosteric Inhibition of NS2B/NS3 Protease and Interference with Host C-Type Lectin Receptor-Mediated Entry

Objective: This study aimed to perform a computational analysis of apigenin and luteolin, focusing on their biological activities, pharmacokinetic properties, and interactions with dengue virus serotype 2 (DENV-2) proteins and host cell receptors associated with viral entry.Material and Methods: The biological activiti...

Siriwan Aroonrungreang, Benjaporn Noppradit, P. Puttarak et al. · 0 citations

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