In vitro and in silico anti-inflammatory investigation of triterpenoids from combretum trifoliatum.
A saponin-enriched extract from the Combretum trifoliatum Vent. leaves (SE-CTL) exhibited notable in vitro anti-inflammatory activity, with an IC50 of 46.39 µg/mL against LPS-induced Nitric Oxide (NO) production in RAW264.7 macrophages. Phytochemical investigation of SE-CTL led to the isolation and structure elucidatio...