Author

N. Parajuli

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Open access Oct 2026

Molecular Docking and Molecular Dynamics Simulation Studies of Human Pancreatic α-Amylase with Phytochemicals from Corydalis chaerophylla D.C.

Diabetes mellitus, a chronic metabolic disorder resulting from hyperglycemia, is responsible for millions of deaths worldwide. The hyperglycemic index can be reduced through the inhibition of human pancreatic α-amylase (HPAA), an enzyme associated with the cleavage of α-(1,4)-D-glycosidic bonds for the conversion of st...

Binita Maharjan, N. Parajuli, T. Shrestha et al. · Amrit Research Journal · 0 citations

Open access Oct 2026

Multi-Omic Analyses Reveal VPS72 Associations with Chromatin Remodeling, Proliferation, and Stress-Response Programs Across Human Cancers

It is shown that VPS72 copy-number gain occurs in more than one-third of tumors and its expression is enriched beyond that expected from neighboring 1q21 genes and remains elevated over normal tissue in copy-neutral tumors.

X. Solone, Md-Selim Reza, Paul A. Renauer et al. · International Journal of Mol... · 0 citations

Open access Oct 2026

Exploring the Bioactive Potential of Ficus benghalensis L. Leaves: Phytochemical Profiling and In Vitro Biological Evaluation

Ficus benghalensis L. (Bar) is a medicinally valued plant containing a diverse range of phytochemical constituents. The present study evaluated the phytochemical profile and biological activities of hexane, chloroform, and methanol leaf extracts obtained by ultrasound-assisted extraction. Phytochemical screening reveal...

Sujita Mali, Kamana Shahi Thakuri, N. Parajuli et al. · Amrit Research Journal · 0 citations