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Author

N. Palei

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Oct 2026

Silymarin loaded hyaluronic acid-coated cubosomal gel for topical delivery: Optimization, characterizations, and ex vivo skin permeation studies.

OBJECTIVE This study aimed to develop a silymarin (SLM) loaded cubosomal gel and coat it with hyaluronic acid on the surface of the optimized formulation to evaluate skin permeation efficiency. METHODS The cubosomes (CBS) was prepared using a top-down method with monoolein, poloxamer 407, and sonication. A Box-Behnke...

Neha Raj, Abhishek Singh, N. Palei et al. · 0 citations
Review Sep 2026

Chitosan-Based Nose-to-Brain Drug Delivery for Management of Neurological Disorders: Intrinsic Neuroprotective Action and Carrier Capabilities

Neurological disorders represent a major global health burden, primarily due to the limited ability of therapeutic agents to cross the blood–brain barrier (BBB). Nose-to-brain (NTB) delivery has emerged as a promising non-invasive strategy to bypass the BBB and directly target the central nervous system (CNS). Among va...

Abhishek Singh, Sourin Bhukta, Deepak Mishra et al. · 0 citations
Review Jul 2026

Exosomes in Neurodegenerative Disorders: Isolation Strategies, Therapeutic Potential, and Clinical Trials.

This review provides an in-depth examination of exosome biogenesis, current isolation methodologies, and surface engineering strategies, while critically evaluating the strengths and limitations of each approach.

Sourin Bhukta, N. Palei, Vishakha Jaiswal et al. · 0 citations

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