N. Obernikhina

Design, synthesis, structural diversity, ADMET profiling and DFT calculations of 1,2,4-oxadiazole-1,3-oxazole hybrids

To obtain new bioactive nitrogen-containing heterocycles, hybrid molecules incorporating two heterocyclic rings as potential dual binding sites for biomolecules were synthesized in this study. The resulting compounds combine 1,2,4-oxadiazole and 1,3-oxazole fragments within a single molecular framework. The starting ma...