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Author

N. Novosolova

2 papers indexed here

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Open access 2026

Electrophysiological analysis of purinergic signaling of microglia as an approach to studying the immune mechanisms of Alzheimer's disease

Neuroinflammation mediated by chronic microglial activation is considered a key factor in the pathogenesis of Alzheimer's disease (AD). Purinergic signaling, particularly P2X4 and P2X7 receptors activated by extracellular ATP, plays an important role in modulating microglial function. Understanding the ionic mechanisms...

G. T. Tasibekova, N. Novosolova, M. K. Zholdasova et al. · 0 citations
Review Open access Aug 2026

Live brain biopsy during CSF shunt surgery for precision diagnostics and multi-omic research

Diagnostic testing and neurosurgical management involving CSF shunting in patients with idiopathic normal pressure hydrocephalus (iNPH) offers a unique, ethically sustainable opportunity to study the aging human brain. The common co-occurrence of neurodegenerative pathologies such as amyloid-β plaques and neurofibril...

Heikki E. M. Lukkarinen, A. Luikku, Antonios Dougalis et al. · 0 citations

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