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Author

N. Nicosia

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Open access Sep 2026

412. Study of behavioural, molecular, morphological and electrophysiological effects of chronic stress in mice

Abstract Background Chronic stress profoundly affects brain function and constitutes a major risk factor for both psychiatric and systemic pathologies. Understanding its impact necessitates an integrated approach linking behavioural, molecular, and neural mechanisms. While biological variables such as sex and circadian...

M. Giovenzana, J. Mingardi, P. Misztak et al. · 0 citations
Open access Sep 2026

452. Primary neuronal cultures to study neuroplastic effects of hallucinogen drugs

Abstract Background Chronic stress is a key risk factor for major depressive disorder (MDD), one of the leading causes of disability worldwide1. Despite available pharmacological therapies, treatment-resistant depression (TRD) remains a clinical challenge. Hallucinogens such as ketamine and serotonergic psychedelics in...

N. Nicosia, J. Mingardi, G. Terribile et al. · 0 citations
Jun 2026

Mutations in the three synapsin genes lead to profound social deficits and cortical dysfunctions.

Results show that synapsin deletion is associated with a distinct profile of social and repetitive behavioral abnormalities, accompanied by a region-selective alteration in IL-mPFC firing activity, which indicates a marked deficit in sociability and social recognition in TKO mice.

Noemi Nicosia, Elena Monzani, Maria Regoni et al. · 0 citations

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